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目的:了解新疆生产建设兵团儿童乙型肝炎血清免疫学状况。方法:采用分层按比例抽样方法随机抽取各年龄组人群,调查后对采集血样进行酶联免疫吸附试验(ELISA)检测,HBsAg、HBsAb。实验结果用SPSS13.0统计软件进行统计学处理。结果:(1)HBsAg阳性率为1.6%(标准化率为2.34%);HBsAb阳性率为60.1%(标准化率为55.33%);(2)HBsAg阳性率7-15岁儿童高于6岁及以下儿童(x2=7.644,P=0.006);HBsAb阳性率7-15岁儿童低于6岁及以下儿童(x2=31.406,P<0.01)。(3)HBsAg、HBsAb阳性率性别间差别没有统计学意义。(4)HBsAg阳性率南疆高于北疆(x2=9.548,P=0.002<0.01)、HBsAb阳性率南疆低于北疆(x2=199.3,P<0.01)。结论:兵团儿童乙型肝炎防治工作在新疆地区取得较好效果,仍低于全国平均水平。
Objective: To understand the status of hepatitis B immunization in children in Xinjiang Production and Construction Corps. Methods: Stratified by proportional sampling method were randomly selected for all age groups, after the investigation of blood samples collected for enzyme-linked immunosorbent assay (ELISA) detection, HBsAg, HBsAb. The experimental results using SPSS13.0 statistical software for statistical analysis. Results: (1) HBsAg positive rate was 1.6% (normalization rate was 2.34%); HBsAb positive rate was 60.1% (standardization rate was 55.33%); (2) HBsAg positive rate was higher in children aged 7-15 years than 6 years old Children (x2 = 7.644, P = 0.006). Children with HBsAb positive rate were lower in children aged 7-15 years than children 6 years old and younger (x2 = 31.406, P <0.01). (3) HBsAg, HBsAb positive rate sex difference was not statistically significant. (4) The positive rate of HBsAg in southern Xinjiang was higher than that in northern Xinjiang (x2 = 9.548, P = 0.002 <0.01). The positive rate of HBsAb in southern Xinjiang was lower than that in northern Xinjiang (x2 = 199.3, P <0.01). Conclusion: Corps children hepatitis B prevention and treatment work in Xinjiang achieved good results, still below the national average.