一、前言各种皮肤病大抵伴有轻重不等的瘙痒症状,而有些皮肤病的瘙痒症状,有时又极为顽固,常使患者精神困扰不已,大脑皮层机能因之受到严重冲突,往往形成疾病发展的恶性循环,使症状加剧,病程延长.同时,瘙痒的机制甚为复杂,目前现代医学尚未能完全阐明,而临床上对止痒多为对症措施,一般常用的止痒药剂的疗效又均短暂,难以满意,因之,积极的寻找具有卓越疗效的止痒疗法,以解决病员痛苦,实为目前皮肤科工作者的主要任务之一。 I. INTRODUCTION A variety of dermatological diseases are associated with pruritus symptoms of varying severity. Some pruritus symptoms of dermatosis are sometimes extremely stubborn and often cause mental distress to patients. Cerebral cortical functions are severely affected by the disease and often lead to the development of diseases Of the vicious circle, so that the symptoms aggravate the course of the disease.At the same time, the mechanism of itching is very complicated, at present, modern medicine has not been fully elucidated, and clinically itchy and mostly symptomatic measures, the commonly used antipruritic agents are Short, difficult to be satisfied with, therefore, actively looking for antipruritic therapy with excellent curative effect to solve the patient’s suffering, in fact, one of the main tasks of dermatologists.