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目的:探讨老年糖尿病应用阿卡波糖、甘精胰岛素联合方案的效果和安全性。方法:随机抽取2015年7月-2016年5月期间我院收治的糖尿病患者74例作对比研究,随机分为对照组(n=37例)和观察组(n=37例),前者单纯应用阿卡波糖治疗,而后者则采用阿卡波糖与甘精胰岛素联合治疗方案,通过对比分析的方式,探讨联合应用方案的有效性。结果:治疗前两组2-HPG、PBG、HbA1c指标水平差异不明显(p>0.05),治疗后2-HPG、PBG、HbA1c指标水平均低于治疗前(p<0.05),而观察组治疗后2-HPG、PBG、HbA1c指标水平明显低于对照组(p<0.05);观察组低血糖发生率方面显著低于对照组(p<0.05)。结论:临床上针对老年糖尿病患者应用阿卡波糖、甘精胰岛素联合方案,可取得较为满意的临床疗效,提高老年人生活质量。
Objective: To investigate the effect and safety of acarbose and insulin glargine in elderly patients with diabetes mellitus. Methods: A total of 74 diabetic patients treated in our hospital from July 2015 to May 2016 were randomly divided into control group (n = 37) and observation group (n = 37) Acarbose treatment, while the latter is the combination of acarbose and insulin glargine regimen, through the comparative analysis of ways to explore the effectiveness of the combination of programs. Results: The levels of 2-HPG, PBG and HbA1c in the two groups before treatment were not significantly different (p> 0.05). The levels of 2-HPG, PBG and HbA1c in the two groups before treatment were lower than those before treatment The levels of 2-HPG, PBG and HbA1c in the observation group were significantly lower than those in the control group (p <0.05). The incidence of hypoglycemia in the observation group was significantly lower than that of the control group (p <0.05). Conclusion: Clinical application of acarbose and insulin glargine in elderly patients with diabetes can achieve satisfactory clinical efficacy and improve the quality of life of the elderly.