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测定了１０例急性脑出血和８例急性蛛网膜下腔出血患者血浆及脑脊液（ＣＳＦ）中β－内啡呔（β－ＥＰ）和强啡呔（ＤｙｎＡ）的含量。结果脑出血组血浆和ＣＳＰ中β－ＥＰ和ＤｙｎＡ含量均显著增高；蛛网膜下腔出血组ＣＳＦ中β－ＥＰ和ＤｙｎＡ增高，血浆中仅β－ＥＰ含量增高，提示这两种内源性阿片肽参与了出血性中风的病理生理过程，并可能是加重其继发性中枢神经系统损害的因素之一。
The levels of β-EP and DynA in plasma and cerebrospinal fluid (CSF) of 10 patients with acute cerebral hemorrhage and 8 patients with acute subarachnoid hemorrhage were measured. Results The levels of β-EP and DynA in the plasma and CSP of patients with cerebral hemorrhage were significantly increased. The levels of β-EP and DynA in the CSF and the increase of β-EP in the plasma were higher in the subarachnoid hemorrhage group, suggesting that the two endogenous opioids Peptides are involved in the pathophysiology of hemorrhagic stroke and may be one of the factors that aggravate the secondary CNS damage.