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目的探讨未足月胎膜早破(PPROM)合并生殖道感染对妊娠结局的影响。方法回顾性分析2012年12月-2015年12月惠州市第一妇幼保健院收治的100例初产单胎PPROM患者的临床资料,其中合并生殖道感染的PPROM患者42例(研究组),单纯PPROM患者58例(对照组),比较两组患者的妊娠结局。结果研究组自然分娩率为69.05%,低于对照组的82.76%,差异无统计学意义(P>0.05);剖宫产和人工辅助阴道分娩率分别为23.81%和11.90%,高于对照组的10.34%和6.90%,差异无统计学意义(P>0.05);早产、宫内窘迫、生长受限和新生儿窒息的发生率比较,差异无统计学意义(P>0.05)。产褥感染、产后出血、绒毛膜羊膜炎和新生儿肺炎的发生率为19.05%、30.96%、14.29%和19.05%,显著高于对照组的3.45%、1.72%、1.72%和3.45%,两组间差异有统计学意义(P<0.05)。结论未足月胎膜早破合并生殖道感染可导致不良的妊娠结局,因此在妊娠期进行生殖道感染筛查,及早诊断,及早行针对性治疗,有助于改善妊娠结局。
Objective To investigate the effect of incomplete premature rupture of membranes (PPROM) combined with genital tract infection on pregnancy outcome. Methods The clinical data of 100 primiparous singleton pregnancies from January 2012 to December 2015 in Huizhou First Maternal and Child Health Hospital were retrospectively analyzed. Among them, 42 cases of PPROM with genital tract infection (study group), simple 58 patients with PPROM (control group), the pregnancy outcome of two groups were compared. Results The rate of spontaneous delivery in study group was 69.05%, which was lower than 82.76% in control group (P> 0.05). The rate of cesarean section and artificial vaginal delivery was 23.81% and 11.90% respectively, which was higher than that of control group (P> 0.05). There was no significant difference in the incidence of preterm birth, intrauterine distress, growth restriction and neonatal asphyxia (P> 0.05). The incidence of puerperal infection, postpartum hemorrhage, chorioamnionitis and neonatal pneumonia were 19.05%, 30.96%, 14.29% and 19.05%, which were significantly higher than those of the control group (3.45%, 1.72%, 1.72% and 3.45% There was significant difference between groups (P <0.05). Conclusions Insufficient premature rupture of membranes combined with genital tract infection can result in poor pregnancy outcomes. Therefore, screening for pregnancy-induced reproductive tract infections, early diagnosis and targeted treatment as early as possible may help to improve pregnancy outcomes.