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目的了解某高职院校新生乙型肝炎病毒(HBV)感染情况。方法对2006级2850名新生采用酶联免疫法(ELISA)检测乙型肝炎病毒标志物(HBVM)。结果某高职院校新生HBsAg阳性率为13.47%,农村、城市学生HBsAg阳性率分别17.83%、10.37%,农村明显高于城市学生(P<0.01),男生高于女生(P<0.01)。HBVM有8种组合模式,其中主要为HBsAg+HBeAg+抗HBc+(35.94%);其次为HBsAg+抗HBe+抗HBc+(28.65%);单纯HBsAb占总检人数7.29%。结论乙肝防治工作中,注意HBsAg阳性感染者时不要忽视HBsAg阴性的HBV感染者。对HBV易感者应及时接种乙型肝炎疫苗并加强监测,必要时复种或加强接种。
Objective To understand the status of hepatitis B virus (HBV) infection in new vocational college. Methods 2850 freshmen in 2006 were tested for hepatitis B virus (HBVM) by enzyme-linked immunosorbent assay (ELISA). Results The HBsAg positive rate of freshmen in a vocational college was 13.47%. The positive rates of HBsAg in rural and urban students were 17.83% and 10.37% respectively. The rural areas were significantly higher than urban students (P <0.01) and boys were higher than girls (P <0.01). There are 8 kinds of combination modes of HBVM, including HBsAg + HBeAg + anti-HBc + (35.94%), followed by HBsAg + anti-HBe + anti-HBc + (28.65%); Conclusion Hepatitis B prevention and control work, pay attention to HBsAg-positive patients do not ignore HBsAg-negative HBV infection. HBV susceptible should promptly inoculated hepatitis B vaccine and strengthen monitoring, if necessary, multiple or intensified vaccination.