钙拮抗剂(Calcium Antagonist,CA)是继β受体阻滞剂之后用于治疗心血管病的一类药物。但在肾脏疾病中的应用,国内还很少见文献报道。为此,本文就这一领域的应用近况作一综述。钙与肾脏损伤的病理生理学迄今已有大量资料证实,许多疾病的肾损害,如子痫、DIC、感染、溶血性尿毒症综合征等都涉及到血栓素 A_2(TXA_2)。TXA_2与它的 Calcium Antagonist (Calcium Antagonist, CA) is a class of drugs used in the treatment of cardiovascular disease after β-blocker. However, the application of kidney disease, the domestic is still rarely reported in the literature. To this end, this article reviews the status of application in this area. Pathophysiology of Calcium and Kidney Injury There has been a large body of evidence to date that thromboxane A 2 (TXA 2) is involved in many diseases, such as eclampsia, DIC, infection, hemolytic uremic syndrome, and many others. TXA_2 with it