2,4,6—三碘雷锁辛(2,4,6—Triiod—oresorcinol)系由苏联药物化学研究所于七十年代首次成合。通过十余年的药效,药理研究以及临床应用,证实该化合物是一种高效低毒的抗霉菌药物。近期,我们以自制的氯化碘钾为碘代剂,制备出2,4,6—三碘雷锁辛。获得了较稳定的制备方法。试制表明:该化合物的制备工艺简单,厚辅料易得,收得率高。 2,4,6-Triiodorealcin (2,4,6-Triiod-oresorcinol) was first synthesized by the Institute of Medicinal Chemistry of the Soviet Union in the seventies. Through more than ten years of pharmacodynamics, pharmacological research and clinical application, it has been proved that the compound is an antifungal drug with high efficiency and low toxicity. Recently, we made homemade iodine potassium iodide iodine agent, prepared 2,4,6-triiodide Lei Suoxin. Obtained a more stable preparation. Trial showed that: the preparation of the compound is simple, easy access to thick materials, high yield.