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为了比较用于检测乙型肝炎 (乙肝 )病毒表面抗原 (HBsAg)的胶体金试纸快速检测法和固相放射免疫检测法(SPRIA) ,2 0 0 2年大同市采用配对比较的方法检测了 0～ 7岁健康儿童的血清 30 9份。结果显示 :胶体金试纸快速检测法 ,阳性检出率为 0 97% ,RIA法的阳性检出率为 3 2 4 %。两种方法阳性检出率的差异有显著的统计学意义(χ2 =5 14 ,P <0 0 5 )。两种方法用于检测HBsAg一致性好 ,但胶体金试纸快速检测法灵敏度较低。采用SPRI A法检测的 30 9份健康儿童血清HBsAg阳性率为 3 2 4 % ,≤ 3岁儿童的血清HBsAg阳性率为 0 ,>3岁儿童的血清HBsAg阳性率为 4 93% ,两组差异有非常显著的统计学意义 (χ2 =6 2 5 ,P <0 0 1)。随着年龄的增加 ,HBsAg阳性率升高。
In order to compare the rapid detection method of gold colloidal gold test strip and solid-phase radioimmunoassay (SPRIA) for the detection of Hepatitis B virus surface antigen (HBsAg), in 2002, Datong City adopted a paired comparison test to detect 0 Seventy nine healthy children aged 7 ~ The results showed that the positive detection rate of colloidal gold test strips was 0 97% and the positive detection rate of RIA method was 3 2 4%. The positive rate of the two methods was significantly different (χ2 = 5 14, P <0 05). Two methods for the detection of HBsAg consistency, but the sensitivity of colloidal gold test strip rapid detection method is low. The positive rate of HBsAg in 30 healthy children detected by SPRI A method was 32.4%, the positive rate of serum HBsAg was 0 in children ≤ 3 years old, and the positive rate of HBsAg was 433% in children> 3 years old. There was significant difference between the two groups There is a very significant statistical significance (χ2 = 625, P <0.01). With age, the positive rate of HBsAg increased.