抗利尿激素分泌不当综合征(SiADH)常伴有与液体摄入呈负相关的血清钠和尿酸浓度的同步改变。SiADH时低尿酸血症大部分是由于肾脏清除尿酸盐增加所致。限制液体摄入可矫正低钠血症、低尿酸血症以及尿酸盐清除的缺陷。 作者报告5例非SiADH的低钠血症与低尿酸血症共存的病人。1例为伴有腹水、水肿、低蛋白血症、低磷血症的转移性胰癌;2例为肺腺癌,其中1例已有脑转移;1例为弥散性隐球菌感染;1例为Hodgkin’s病。上述病例在接受研究前至少4 Improper secretion of anti-diuretic hormone syndrome (SiADH) is often accompanied by a synchronous change in serum sodium and uric acid concentrations that are negatively correlated with fluid intake. Most of the hypoacidosis during SiADH is due to an increase in renal clearance urate. Limiting fluid intake corrects for hyponatremia, hypouria, and urate clearance. The authors report 5 patients with non-SiADH hyponatremia and low uric acid coexist patients. 1 case of metastatic pancreatic cancer with ascites, edema, hypoproteinemia, hypophosphatemia; 2 cases of lung adenocarcinoma, of which 1 case had brain metastases; 1 case of diffuse cryptococcal infection; 1 case For Hodgkin’s disease. The above cases were at least 4 prior to receiving the study