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目的对比分析汉族与维吾尔族妇女妊娠期糖尿病(gestational diabetes mellitus,GDM)的妊娠结局。方法回顾性分析作者医院内分泌科及产科2011-05/2013-05月诊治的GDM患者105例,其中汉族组57例(GDM汉族组),维吾尔族组48例(GDM维吾尔族组),对照组为妊娠期糖代谢正常孕妇121例。对比这3组妊娠结局的差异。结果GDM汉族组的年龄、孕前体质量及巨大儿发生率均明显大于对照组(P<0.05);GDM维吾尔族组的年龄、孕前体质量、分娩体质量、早产率及巨大儿发生率,均明显高于对照组(P<0.05)。GDM维吾尔族组的早产率和巨大儿发生率均显著高于GDM汉族组(P<0.05)。结论 GDM患者,孕妇和新生儿的不良事件发生率均高于对照组;在GDM患者中,维吾尔族孕妇较汉族孕妇更易发生妊娠相关不良事件。
Objective To compare the pregnancy outcomes of gestational diabetes mellitus (GDM) between Han and Uygur women. Methods A retrospective analysis of 105 cases of GDM patients diagnosed and treated in Department of Endocrinology and Obstetrics of the Hospital from May 2011 to May 2013 was conducted. Among them, 57 Han patients (GDM Han nationality), 48 Uygur patients (GDM Uygur nationality) and control group 121 cases of normal pregnant women with glucose metabolism during pregnancy. Comparison of these three groups differences in pregnancy outcomes. Results The age, pre-pregnancy weight and the incidence of macrosomia in GDM Han nationality group were significantly higher than those in control group (P <0.05). The mean age, pre-pregnancy weight, birth weight, premature birth rate and macrosomia in GDM Uighur group were Significantly higher than the control group (P <0.05). The rates of preterm birth and macrosomia in GDM Uighur group were significantly higher than those in GDM Han (P <0.05). Conclusions The incidence of adverse events in GDM patients, pregnant women and newborns is higher than that in the control group. Among the GDM patients, Uighur pregnant women are more likely to have pregnancy-related adverse events than Han pregnant women.