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甲状腺机能减退症(甲减)是~(131)I 治疗毒性甲状腺肿的一种并发症,最近研究表明,小剂量~(131)I 治疗后甲减的发病率亦高,且延续至治疗后25年。为此,甲减的早期诊断,治疗及密切随访极为重要。人们认为大剂量~(131)I 加之甲状腺替代疗法不易立即引起甲减,而甲状腺替代疗法具有价廉、患者易于监护之优点。作者进行了放射性碘治疗毒性甲状腺肿的多年研究,其目的是早期发现甲减、选择最佳的~(131)I 剂量和掌握放射性~(131)I 治疗的影响因素。本文1962年～1982年治疗了毒性甲状腺肿1168例(男性302例,女性866例),年龄分布为24～85岁。其中弥漫型占58.4%,结节型30.1%,小结节型占11.5%。
Hypothyroidism (hypothyroidism) is a complication of ~ (131) I in the treatment of toxic goiter. Recent studies have shown that the incidence of hypothyroidism after low dose 131I treatment is also high and continues until after treatment 25 years. To this end, hypothyroidism early diagnosis, treatment and close follow-up is extremely important. It is believed that high doses of 131I combined with thyroid replacement therapy are not immediately cause hypothyroidism, and thyroid replacement therapy is inexpensive and patient-friendly. The aim of the study was to find hypothyroidism early, to select the best dose of 131 I, and to study the influencing factors of 131I treatment. This article from 1962 to 1982, the treatment of 1168 cases of toxic goiter (302 males and 866 females), the age distribution of 24 to 85 years old. Among them diffuse type accounted for 58.4%, nodular type 30.1%, nodular type accounted for 11.5%.