急性早幼粒细胞白血病(APL)是一种具有特殊染色体t(15;17)异位形成PML-RARα融合基因的急性髓系白血病,发病急,病情进展迅速,易并发感染及弥漫性血管内凝血,早期死亡率较其他亚型急性髓系白血病高。全反式维甲酸(ATRA)和砷剂(As2O3)应用,显著提高了APL缓解率和生存率。西苑医院 Acute promyelocytic leukemia (APL) is an acute myeloid leukemia with a special chromosomal t (15; 17) that forms the PML-RARα fusion gene ectopically. The incidence of acute myeloid leukemia is very high. The disease progresses rapidly and is prone to complicated infection and disseminated intravascular Coagulation, early mortality rate than other subtypes of acute myeloid leukemia. All-trans retinoic acid (ATRA) and arsenic (As2O3) application, significantly improved APL remission rate and survival rate. Xiyuan Hospital