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目的:分析研究早发型子宫内膜癌的临床特点,为临床诊治提供参考。方法:选取2002年7月至2014年7月间收治的16例早发型(年龄低于45岁)子宫内膜癌患者作为早发型组,选取同期收治的16例普通型子宫内膜癌患者作为对照(普通组,年龄高于45岁),比较两组患者的临床表现、临床特征与病理类型。结果:1早发组与普通组在贫血方面对比存在较大差异,早发组贫血情况明显高于普通组,差异有统计学意义(P<0.05)。2两组患者在附件累及、宫颈累及、与腹水细胞学检查方面对比无统计学意义(P>0.05)。3早发组G1分化所占比重明显高于普通组,差异有统计学意义(P<0.05)。4两组患者在病理分期上具有统计学意义(P<0.05)。结论:早发型子宫内膜癌的产生与患者月经生育史、年龄有着较大关联,未绝经的患者分期早,治疗效果更好。
Objective: To analyze the clinical features of early-onset endometrial carcinoma and provide reference for clinical diagnosis and treatment. Methods: Sixteen patients with early-onset endometrial carcinoma (aged below 45 years) who were admitted to our hospital from July 2002 to July 2014 were selected as early-onset group and 16 patients with endometrial carcinoma Control (general group, age 45 years old), the clinical manifestations, clinical features and pathological types of two groups were compared. There was significant difference in anemia among early-onset group and general group, anemia in early-onset group was significantly higher than that in normal group (P <0.05). 2 The two groups of patients involved in attachment, cervical involvement, and ascites cytology comparison was not statistically significant (P> 0.05). The proportion of G1 differentiation in early onset group was significantly higher than that in normal group, the difference was statistically significant (P <0.05). 4 The two groups of patients in the pathological staging were statistically significant (P <0.05). Conclusion: The incidence of early-onset endometrial cancer is closely related to the history of menstruation and the age of patients. The patients with non-menopausal stage have earlier stage and the treatment effect is better.