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目的:探讨慢性戊型病毒性肝炎合并急性乙型病毒性肝炎的发病机制、诊断、治疗及其预后。方法:回顾我院收治的一例慢性戊型病毒性肝炎合并急性乙型病毒性肝炎患者的临床资料,并结合文献探讨戊型病毒性肝炎及乙型病毒性肝炎的发病机制,总结其诊断及治疗经验,并评价其预后。结果:该患者戊肝抗体长期阳性,被诊断为慢性戊型病毒性肝炎,但合并急性乙型病毒性肝炎后,经治疗乙肝表面抗原转阴后戊肝抗体Ig M也阴转。结论:慢性戊型病毒性肝炎合并急性乙型病毒性肝炎患者经治疗后可同时出现乙肝表面抗原转阴,戊肝抗体阴转,预后可较好。
Objective: To investigate the pathogenesis, diagnosis, treatment and prognosis of chronic viral hepatitis with acute viral hepatitis B. Methods: The clinical data of one patient with chronic hepatitis E and acute hepatitis B admitted to our hospital were retrospectively reviewed. The pathogenesis of hepatitis E and hepatitis B was discussed in combination with the literature, and its diagnosis and treatment were summarized Experience, and evaluate the prognosis. Results: Hepatitis E antibody of this patient was long-term positive and was diagnosed as chronic hepatitis E virus. However, after combined treatment of acute hepatitis B virus, IgM of hepatitis E antibody was also negative after treatment of HBsAg negative. Conclusion: Patients with chronic viral hepatitis and acute viral hepatitis B may be treated with hepatitis E surface antigen negative, hepatitis E antibody negative conversion, the prognosis may be better.