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目的 总结革兰阳性细菌医院内获得性支气管-肺感染临床情况。方法分析80例患者的年龄、发病时间、基础疾病、诱发因素、临床表现,病原菌耐药性及预后。结果 平均年龄58.2± 20.5岁,发病时间为19.1± 17.1d,慢性阻塞性肺病是最常见的基础疾病。接受肾上腺皮质激素治疗、化疗和主要针对革兰阴性细菌的抗生素治疗是可能的诱发因素。临床表现缺乏特征性。葡萄球菌属68株(80%),其中耐苯唑西林的金葡菌29株(耐药率29/33,87.9 %),耐苯唑西林凝固酶阴性的葡萄球菌25株(耐药率25/35,71.4%)。死亡率38.8%。结论 革兰阳性细菌医院内获得性支气管-肺感染耐药菌株多,死亡率高,值得重视。
Objective To summarize the clinical situation of acquired bronchopulmonary infection in Gram-positive bacteria hospital. Methods 80 patients were analyzed for their age, onset time, underlying diseases, predisposing factors, clinical manifestations, pathogen resistance and prognosis. Results The average age was 58.2 ± 20.5 years and the onset time was 19.1 ± 17.1 days. Chronic obstructive pulmonary disease was the most common underlying disease. Corticosteroid therapy, chemotherapy, and antibiotic therapy that target primarily gram-negative bacteria are possible triggers. Clinical manifestations lack character. Staphylococcus 68 strains (80%), which resistant to oxacillin 29 Staphylococcus aureus (resistance rate 29 / 33,87.9%), resistant to oxacillin coagulase-negative Staphylococcus 25 (resistant Rate 25/35, 71.4%). The mortality rate was 38.8%. Conclusion Gram-positive bacteria in hospital acquired bronchial-lung infection resistant strains, high mortality, it is worth attention.