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系统性红斑狼疮(systemic lupus erythematosus,SLE)是自身免疫介导的,以免疫炎症为突出表现的弥漫性结缔组织病。血清中出现以抗核抗体为代表的多种自身免疫抗体和多系统累及是SLE的两大特点[1]。而结核病是呼吸道传染病,人体感染结核分枝杆菌后是否发病与免疫功能密切相关。临床上常见SLE患者因应用大量糖皮质激素(简称激素)或免疫抑制剂后继发结核感染或结核活动的病例。现将SLE与结核病的关系及临床特点介绍如下,以引起相关专业临床大夫的重视,
Systemic lupus erythematosus (SLE) is an autoimmune-mediated, diffuse connective tissue disease characterized by immune inflammation. A variety of autoimmune antibodies represented by antinuclear antibodies and multiple system involvement in serum are two major characteristics of SLE [1]. The tuberculosis is a respiratory disease, the human body infected with Mycobacterium tuberculosis is closely related to the immune function. Clinically common in patients with SLE due to the application of a large number of glucocorticoid (hormone) or immunosuppressive agents secondary to tuberculosis infection or tuberculosis activity cases. Now the relationship between SLE and tuberculosis and clinical features are introduced below to attract the attention of the relevant professional clinical doctor,