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为探讨丙型肝炎病毒（ＨＣＶ）母婴间垂直传播，对６４例抗ＨＣＶ（＋）和／或ＨＣＶＲＮＡ（＋）孕妇分娩的６５例新生儿取出生当时脐静脉血，用ＥＬＩＳＡ检测抗ＨＣＶ，用逆转录ＰＣＲ检测ＨＣＶＲＮＡ。结果：ＨＣＶＲＮＡ（＋）孕妇，无论抗体阳性与否，垂直传播率９３９％，合并ＡＬＴ增高者，新生儿多ＡＬＴ增高。ＨＣＶＲＮＡ（－），抗ＨＣＶ（＋）孕妇，新生儿抗ＨＣＶ检出率１００％，但ＲＮＡ未检出（＋），不能作为感染ＨＣＶ的依据。结论：ＨＣＶ确实存在母婴垂直传播。
In order to explore the vertical transmission of hepatitis C virus (HCV) between maternal and infant, umbilical cord blood was collected from 64 newborns with anti-HCV (+) and / or HCV RNA (+) Anti-HCV, HCV RNA by reverse transcription PCR. Results: HCV RNA (+) pregnant women, regardless of antibody positive or not, the vertical transmission rate of 93 9%, with elevated ALT, neonatal ALT increased. HCV RNA (-), anti-HCV (+) pregnant women, neonatal anti-HCV detection rate of 100%, but the RNA was not detected (+), can not be used as a basis for HCV infection. Conclusion: HCV does have vertical transmission between mother and baby.