有机磷农药能强烈抑制体内的胆碱酯酶,进入体内的有机磷化合物与胆碱酯酶结合形成磷酰化胆碱酯酶,使胆碱酯酶失去活性,失去催化水解乙酰胆碱的生理功能,造成体内乙酰胆碱积聚,作用于胆碱神经节后纤维所支配器官,引起神经功能紊乱。乙酰胆碱作用于植物神经节,肾上腺髓质和骨胳肌的神经终板上,对这些器官组织起兴奋作用或发生抑制作用。 Organophosphorus pesticides can strongly inhibit the body of cholinesterase, enter the body of organic phosphorus compounds and cholinesterase to form phosphoryl cholinesterase, cholinesterase loss of activity, loss of catalytic hydrolysis of acetylcholine physiological function, Resulting in the accumulation of acetylcholine in the body, the role of cholinergic ganglion fibers dominated by the organ, causing neurological disorders. Acetylcholine acts on the nerve endogas of the autonomic ganglia, adrenal medulla, and skeletal muscle, stimulating or inhibiting these organ tissues.