1997—2011年中国成年居民腰围变化对血压影响的队列研究

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目的探讨中国成年居民腰围变化对血压及高血压发病的影响。方法利用“中国健康与营养调查”数据,选择参加1997年调查并且在2011年被随访到的有完整体格测量资料的18~65岁成年居民为研究对象。运用多元线性回归模型分析腰围变化对血压值的影响,运用Logistic回归模型分析腰围变化对高血压发病的影响。结果与1997年比较,2011年中国18~39岁年龄组男性和女性腰围分别增加9.1和7.8 cm,40~65岁年龄组分别增加5.5和6.6 cm,18~39岁年龄组均较40~65岁年龄组增加明显,差异有统计学意义(P<0.05)。多元线性回归结果显示,18~39岁成年居民腰围变化与收缩压和舒张压变化有正向关系,且与收缩压变化关系较舒张压变化明显;而在40~65岁成年居民中,腰围变化与舒张压变化关系显著。Logistic回归结果显示,当腰围变化作为连续性变量进入模型时,腰围每增加1 cm,18~39岁年龄组和40~65岁年龄组高血压的发病风险分别增加5%和4%;当腰围变化以四分位数形式进入模型时,第四分位与第一分位相比,高血压的发病风险明显增加(18~39岁年龄组OR=2.56,95%CI 1.56~4.22;40~65岁年龄组OR=2.84,95%CI 1.77~4.57)。结论腰围变化与血压变化存在正相关关系,18~39岁年龄组较40~65岁年龄组显著,前者主要作用于收缩压变化,后者主要作用于舒张压变化,腰围增加可显著增加高血压的发病风险。 Objective To investigate the effect of waist circumference changes on the incidence of hypertension and blood pressure in adult Chinese residents. Methods According to the “China Health and Nutrition Survey” data, 18-65-year-old residents with complete physical measurement data who participated in the survey in 1997 and were followed up in 2011 were selected as the study subjects. Multivariate linear regression model was used to analyze the influence of waist circumference on blood pressure. Logistic regression model was used to analyze the influence of waist circumference on the incidence of hypertension. Results Compared with 1997, the waist circumference of males and females in China aged 18-39 increased by 9.1 and 7.8 cm in 2011, 5.5 and 6.6 cm in age groups of 40-65, respectively, while those in 18-39 age groups were 40-65 The age group increased significantly, the difference was statistically significant (P <0.05). Multivariate linear regression analysis showed that the change of waist circumference was positively correlated with the change of systolic pressure and diastolic pressure in adults aged 18-39 years, and the change of systolic pressure was more obvious than that of diastolic pressure. In the adult population aged 40-65 years, the change of waist circumference And changes in diastolic pressure significant. Logistic regression analysis showed that when waist circumference was used as a continuous variable to enter the model, the risk of hypertension in 18-39 age group and 40-65 age group increased by 5% and 4% respectively for every 1 cm of waist circumference. When waist circumference When the change entered the model as a quartile, the fourth quintile had a significantly increased risk of developing hypertension (OR = 2.56, 95% CI 1.56 to 4.22; 40 to 65 Age group OR = 2.84,95% CI 1.77 ~ 4.57). Conclusion There is a positive correlation between changes of waist circumference and blood pressure. The age of 18-39 age group is significantly higher than that of 40-65 age group. The former mainly plays a role in the change of systolic pressure. The latter mainly acts on the change of diastolic pressure. Increased waist circumference can significantly increase the incidence of hypertension The incidence of risk.
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