外科和内窥镜治疗对血管畸形所致的消化道出血是无效的。作者选取上述病人,用雌-孕酮作双盲、对照、交叉临床试验,以检测其临床效果。病人10例,其中4男,6女,年龄65～89岁。有反复消化道出血史1年以上而近2月需要输血者;内窥镜证实有非特异性多血管畸形者;内窥镜和X线未发现其他出血原因者列为观察对象。凡有妊娠、乳腺或妇科肿瘤、严重肝病或复发性血栓病、男性患者年 Surgical and endoscopic treatment of vascular malformations caused by gastrointestinal bleeding is ineffective. The authors selected the patients and used estrogen-progesterone as a double-blind, controlled, crossover clinical trial to test their clinical outcome. 10 patients, of which 4 men and 6 women, aged 65 to 89 years. Have a history of repeated gastrointestinal bleeding for more than 1 year and nearly 2 months need blood transfusion; endoscopy confirmed non-specific vascular malformations; endoscopy and X-ray found no other causes of bleeding were observed. Where there is pregnancy, breast or gynecological cancer, severe liver disease or recurrent thrombosis, male patient years