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黄荆子(Vitex negundo L.var.cannabifolia的果实)注射液经644例临床观察,证明对急、慢性胆囊炎、胆石症等疾病有较好的镇痛效果,我们对黄荆子注射液药理作用的研究发现:以“热板法”测定,小鼠腹腔注射该药,剂量10克(原生药)/公斤,能显著提高动物对热刺激的痛阈,30分钟可出现镇痛高峰,但较10毫克/公斤吗啡的作用低1.4～2.4倍。60分钟时作用减弱,镇痛作用持续两小时左右。同时可延长戊
The Vitex negundo L. var. cannabifolia fruit injection was clinically observed in 644 cases and proved to have good analgesic effect on acute and chronic cholecystitis, cholelithiasis and other diseases. Our study on the pharmacological effects of Vitex negundo injection : As determined by the “hot plate method”, the mice were injected intraperitoneally with a dose of 10 g (native drug)/kg, which can significantly increase the animal’s pain threshold for thermal stimuli, and peak analgesia can be seen within 30 minutes, but it is 10 mg/l. The effect of morphine kg is 1.4-2.4 times lower. The effect diminished at 60 minutes and the analgesic effect continued for about two hours. While extending the E