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氨基磺酸作为一种可回收、绿色催化剂在室温下能高效地催化合成β-乙酰氨基酮。反应产物通过红外、1H NMR和13C NMR表征,其结果证明为合成的目标分子.特别值得强调的是二元官能团的β-乙酰氨基酮也可通过乙酰氯、苯乙酮、间苯二甲醛和腈类化合物交联得到.而且二元官能团的β-乙酰氨基酮的催化合成很少见报导.在氨基磺酸催化的酮、芳醛、乙酰氯和乙腈参与的多组分反应体系中,反应有条件温和、产率较高、催化剂用量少、催化剂可以回收再利用等优势.
Aminosulphonic acid as a recyclable, green catalyst can efficiently catalyze the synthesis of β-acetylaminone at room temperature. The reaction products were characterized by infrared, 1H NMR and 13C NMR and the results proved to be synthetic target molecules.It is particularly worth emphasizing that the bifunctional β-acetylamino ketones can also be obtained by the reaction of acetyl chloride, acetophenone, isophthalaldehyde and Nitrile compounds obtained cross-linked and bifunctional catalytic synthesis of β-acetylamino ketone is rarely reported in the sulfamic acid catalyzed ketone, aromatic aldehydes, acetyl chloride and acetonitrile in the multi-component reaction system, the reaction Conditional mild, high yield, less catalyst, the catalyst can be recycled and other advantages.