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目的探讨早发型重度子痫前期及期待治疗对妊娠结局的影响。方法选择妊娠≤34周的早发重度子痫前期病例90例,根据发病行保守治疗的孕周分成A组<28周23例;B组28～31周30例和C组32～34周37例。分析孕期治疗时限,孕妇并发症(包括肝功能受损、肾功能受损、心衰、脑血管意外、胎盘早剥、子痫等),胎儿及围产儿结局(包括胎儿窘迫、胎死宫内、新生儿窒息等)。结果三组中孕妇各并发症的发生率差异无统计学意义。A组与B、C组的围产结局差异有统计学意义。结论早发型重度子痫前期在终止妊娠前短期的保守治疗是安全有效的,能明显减少围产儿死亡率及提高生成率,发病孕周早围产儿预后差。
Objective To investigate the effect of early onset severe preeclampsia and expectant treatment on pregnancy outcome. Methods Ninety pregnant women with severe preeclampsia who were ≤34 weeks of pregnancy were divided into two groups according to their conservative gestational age: group A (28 weeks), group B (28 weeks to 31 weeks), group C (group B: 28 to 31 weeks), group C example. Analysis of pregnancy duration of treatment, complications of pregnant women (including impaired liver function, impaired renal function, heart failure, cerebrovascular accident, placental abruption, eclampsia, etc.), fetal and perinatal outcomes (including fetal distress, , Neonatal asphyxia, etc.). Results There was no significant difference in the incidence of complications among pregnant women in the three groups. There was significant difference in perinatal outcome between group A and group B and group C. Conclusions Early conservative treatment of early-onset severe preeclampsia before termination of pregnancy is safe and effective, which can significantly reduce perinatal mortality and increase the incidence of preeclampsia.