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以脑水含量、局部脑血流（ｒＣＢＦ）、全血血小板聚集、心输出量（ＣＯ）、每搏出量（ＳＶ）、心率（ＨＲ）、平均血压（ＭＡＰ）、外周总阻力（ＴＰＲ）及心、肝、脾。肾和肾上腺局部血流量（ｒＢＦ）为指标，探讨光化学法诱导的实验注血栓形成性局部脑缺血时全血血小板功能改变对心功能的影响及其机理。结果表明，光化学反应后４小时，全血血小板聚集明显增强（ｐ＜０．０１），ＣＯ、ＳＶ降低（ｐ＜０．０５）；２４小时ｒＣＢＦ、ＣＯ、ＳＶ及心肌ｒＢＦ均明显减少，ＴＰＲ及脑水含量明显增加（ｐ＜０．０１）；２４小时后，心血管指标的改变随血小板聚集的减弱而逐渐恢复至对照水平。提示血小板功能改变在脑血栓形成所致心功能异常中起重要作用。
Cerebral blood flow, regional cerebral blood flow (rCBF), whole blood platelet aggregation, cardiac output (CO), stroke volume (SV), heart rate (HR), mean blood pressure (MAP), total peripheral resistance (TPR) And heart, liver and spleen. Kidney and adrenal blood flow (rBF) as an indicator to explore the photochemical method induced thrombolytic cerebral ischemia in whole blood platelet function changes on cardiac function and its mechanism. The results showed that at 4 hours after the photochemical reaction, whole blood platelet aggregation increased significantly (p <0.01), CO and SV decreased (p <0.05), rCBF, CO, SV and myocardial rBF decreased significantly And brain water content increased significantly (p <0.01). After 24 hours, the change of cardiovascular index gradually recovered to the control level with the decrease of platelet aggregation. Suggesting that changes in platelet function plays an important role in abnormal cardiac function caused by cerebral thrombosis.