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急性毒鼠强中毒(Acute tetramine intoxication,ATI),一般多凭临床症状和毒物接触史诊断,目前尚无特效解毒剂,病死率高。我们自2000年1月对收治的12例ATI患者均在常规治疗方法的基础上应用床边血液灌流(HP)治疗,结果满意。1 资料与方法1.1 临床资料本文入选的病例均系1998年7月至2001年6月期间收住院救治的中、重度的ATI患者,共23例。2000年12月底前11例为对照组,其后至2001年6月底前12例为治疗组。两组男女之比分别为1:1.20和1:1.40;平均年龄为22.3岁和22.6岁;两组患者均经口中毒,剂量均无法计量;中、重度中毒分度患者之比为1:1.5和1:1.4;发病至就诊时间均为45±15分钟。两组患者发病前均体健,
Acute tetramine intoxication (Acute tetramine intoxication, ATI), generally based on the clinical symptoms and the history of exposure to poison, there is no specific antidote, high mortality. We since January 2000 for the treatment of 12 cases of ATI patients are based on conventional treatment methods based on bedside hemoperfusion (HP) treatment, the results were satisfactory. 1 Materials and Methods 1.1 Clinical data The selected cases were selected from July 1998 to June 2001 admitted to hospital for treatment of moderate and severe ATI patients, a total of 23 cases. Eleven patients before the end of December 2000 were control groups, and 12 patients before the end of June 2001 were treated groups. The ratio of male to female in two groups was 1: 1.20 and 1: 1.40, respectively. The average age was 22.3 years and 22.6 years. The patients in both groups were orally poisoned and the dosage could not be measured. The ratio of moderate to severe poisoning patients was 1: 1.5 And 1: 1.4; onset to treatment time were 45 ± 15 minutes. Two groups of patients before the onset of physical health,