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目的探讨慢性前列腺炎的细菌学病因,为临床治疗提供帮助。方法前列腺检测标本取自140例猝死的器官捐献者,年龄20~35岁。取前列腺周围带组织,分成两块,一块作常规病理检查,另一块用聚合酶链反应检测细菌16S rRNA基因。结果32.9%(46/140)的组织病理呈慢性前列腺炎,均为轻度灶性炎症改变,其中间质炎42例,间质伴腺体周围炎3例,腺体周围炎1例。16SrDNA阳性率为19.3%(27/140),其中前列腺炎标本阳性率为48.9%(22/46),非前列腺炎标本阳性率为5.3%(5/94),前列腺炎标本阳性率高于非前列腺炎标本,差异有统计学意义(χ2=36.910,P<0.001)。结论细菌感染可能是引起慢性前列腺炎的重要原因。
Objective To investigate the bacteriological causes of chronic prostatitis and to provide help for clinical treatment. Methods Prostate specimens were obtained from 140 sudden death organ donors aged 20-35 years. Take the surrounding prostate tissue, divided into two, one for routine pathology, the other with polymerase chain reaction to detect bacterial 16S rRNA gene. Results 32.9% (46/140) of the histopathology showed chronic prostatitis, all of which were mild focal inflammatory changes. There were 42 cases of interstitial inflammation, 3 cases of interstitial and glandular inflammation and 1 case of glandular inflammation. The positive rate of 16SrDNA was 19.3% (27/140). The positive rate of prostatitis specimens was 48.9% (22/46), that of non-prostatitis specimens was 5.3% (5/94), and the positive rate of prostatitis specimens was higher than that of non-prostatitis specimens Prostatitis specimens, the difference was statistically significant (χ2 = 36.910, P <0.001). Conclusion Bacterial infection may be an important cause of chronic prostatitis.