肾损伤是指各种病因造成的肾小球或肾小管结构或功能障碍,最初并无肾小球滤过率(GFR)下降,但发展到一定阶段可导致严重后果。肾损伤症状隐匿,早期临床表现及常规检测指标多不典型,常因难于发现而贻误病情。随着围产医学的发展、危重病人救治成功率的上升,新生儿肾损害的发生率较前有所增高。改善肾功能检测手段,早期发现新生儿肾功能损害并及时给予治疗,对降低病死率、改 Renal injury refers to the glomerular or tubular structure or dysfunction caused by a variety of causes and initially has no reduction in glomerular filtration rate (GFR), but development to a certain stage can result in serious consequences. Kidney injury symptoms hiding, early clinical manifestations and routine detection of multi-atypical, often difficult to find and delaying the disease. With the development of perinatal medicine, the success rate of treatment of critically ill patients increased, the incidence of neonatal renal damage than the previous increase. Improve renal function testing means, early detection of neonatal renal dysfunction and timely treatment, reduce mortality, change