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作者对32例多发性骨髓瘤及22例反应性浆细胞增多症的骨髓浆细胞,进行了电子显微镜的观察与比较,发现核浆发育不平衡、胞浆发育障碍和核的发育异常,在识别肿瘤性浆细胞方面有一定价值。反应性浆细胞增多症的骨髓浆细胞,核常偏位,核浆比率低,核染色质密集,分播于核的周围,多无核仁或小而不明显;胞浆有丰富的粗面内质网,常平行排列,偶而扩张,充满无定形物质,构成蛋白质样包涵体,球形样大小不一,有膜结构所包绕。有些患者可
The author of 32 cases of multiple myeloma and 22 cases of reactive plasma cell hyperplasia of bone marrow plasma cells were observed and compared electron microscopy and found that the uneven development of nuclear and cytoplasm cytoplasm development disorders and nuclear abnormalities in the identification Neoplastic plasma cells have some value. Reactive plasmacytoma of bone marrow plasma cells, the nuclear nuclear deviation, nuclear ratio of nuclear low nuclear chromatin-intensive, distributed around the nucleus, mostly without nucleoli or small but not obvious; cytoplasm rich in rough Endoplasmic reticulum, often arranged in parallel, occasionally expansion, filled with amorphous material, forming protein-like inclusion bodies, spherical samples of different sizes, surrounded by membrane structure. Some patients can