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目的 评估术中细针穿刺细胞学检查对胰腺肿瘤的诊断价值。方法 回顾性分析62例胰腺肿瘤的术中细针穿刺细胞学检查、术中冰冻切片和手术探查、术后病理、术后随访的资料。结果 48例 (77.4% )胰腺肿瘤为恶性 ,14例 (2 2 .6% )为良性。细针穿刺细胞学检查和术中冰冻切片病理诊断胰腺癌的敏感性分别是 77.1%和 60 .4% ,精确度分别为 82 .3 %和 69.4% ,特异性均为 10 0 % ,两种方法差异无显著性 (P >0 .0 5 )。细针穿刺细胞学检查和术中冰冻切片病理检查联合诊断的敏感性和精确度为 87.5 %和 90 .3 % ,高于单一的诊断方法 (P <0 .0 5 )。结论 术中细针穿刺细胞学检查是判断胰腺肿瘤性质快速、简便、安全、有效的方法 ,具有较高的敏感性和特异性 ,与术中冰冻切片病理检查联合应用可进一步提高诊断的敏感性和精确性。
Objective To evaluate the value of intraoperative fine needle aspiration cytology in the diagnosis of pancreatic tumors. Methods A retrospective analysis of 62 cases of pancreatic tumors by intraoperative fine needle aspiration cytology, intraoperative frozen section and surgical exploration, postoperative pathology, postoperative follow-up data. Results 48 cases (77.4%) of pancreatic tumors were malignant and 14 cases (22.6%) were benign. The sensitivity of fine needle aspiration cytology and intraoperative frozen section pathology in the diagnosis of pancreatic cancer were 77.1% and 60.4%, respectively, with the accuracy of 82.3% and 69.4%, specificity of 100% There was no significant difference in the methods (P> 0.05). The sensitivity and accuracy of the combination of fine needle aspiration cytology and intraoperative frozen section biopsy were 87.5% and 90.3%, respectively, higher than the single diagnostic method (P <0.05). Conclusion Intraoperative fine needle aspiration cytology is a rapid, simple, safe and effective method for judging pancreatic tumor with high sensitivity and specificity. Combined with intraoperative frozen section biopsy can further improve the diagnostic sensitivity And accuracy.