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应用兔肺泡巨噬细胞测试系统，选用细胞半数致死浓度（ＬＣ_（５０））、乳酸脱氢酶活性和细胞培养液中的~（５１）Ｃｒ释放量等指标，研究了ＧＢＷ０４１０４（Ｎｏ．４和ＧＢＷ０４１０５（Ｎｏ．５）两种标准铀矿样粉的细胞毒性，并与国产标准石英（Ｑ，ｓ）进行了比较。结果：Ｑ，ｓ、Ｎｏ．５、Ｎｏ．４的ＬＣ_（５０）依次为０．０７２、０．２０１、０．３４４ｍｇ／ｍ１；综合毒性指数（ＣＴＩ）依次为１．００００、０．６０９３、０．３５６６，为定量评价粉尘样品的细胞毒性提供了初步依据。
Rabbit pulmonary alveolar macrophages test system was used to determine the half-lethal concentration (LC_ (50)), lactate dehydrogenase (LDH) activity and the release of ~ (51) Cr in cell culture medium. The effects of GBW04104 GBW04105 (No.5), and compared with domestic standard quartz (Q, s) .Results: LC_ (50) of Q, s, 0.017,0.201,0.344mg / ml. The comprehensive toxicity index (CTI) was 1.0000,0.6093,0.3566, which provided a preliminary basis for the quantitative evaluation of the cytotoxicity of dust samples.