本文探讨了成骨不全病因及其主要遗传特性。笔者按Sillence(1979)的四型分类特征 ,对一家系进行调查分析 ,共 2 2人 ,患者 8人 ,男女同患 ,确定该家系中此病的遗传方式为常染色体显性遗传并归为Ⅰ型。文中根据临床和X线表现进行治疗和遗传咨询劝告 ,并对病因进行了讨论。 This article explores the causes of osteogenesis imperfecta and their major genetic traits. The author according to Sillence (1979) of the four types of classification features of a pedigree investigation and analysis of a total of 22 people, 8 patients, men and women with the same disease, determine the pedigree of the disease is autosomal dominant and inherited Type Ⅰ The article based on clinical and X-ray findings of treatment and counseling counseling, and the etiology were discussed.