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采用琼脂二倍稀释法测定了头孢他啶钠 (CAZ)与他唑巴坦钠 (TAZ)分别以 2∶1、3∶1、4∶1联用对临床分离 4 45株致病菌 (其中产ESBls 34株 ;产酶菌 30 1株 ,非产酶菌 1 1 1株 )的体外抗菌活性 ;并评价其对小鼠实验性细菌感染全身败血症模型的体内疗效 ,同类产品的哌拉西林 /他唑
A total of 455 pathogenic bacteria (ESBls producing ESBLs) were isolated from ceftazidime (CAZ) and tazobactam sodium (TAZ) by 2: 1, 3:1, 34 strains, 30 strains of enzyme-producing bacteria, 11 non-producing strains of bacteria) in vitro antibacterial activity; and evaluation of mice in vivo bacterial sepsis model of bacterial infection in vivo efficacy of similar products piperacillin / tazobactam