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目的:探讨血浆降钙素基因相关肽含量与支气管哮喘急性发作的关系。方法:测定支气管哮喘急性发作和缓解期血浆降钙素基因相关肽的含量,并设正常对照。结果:支气管哮喘急性发作组血浆降钙素基因相关肽显著升高,与缓解组及正常对照组比较差异非常显著(P<0.001),同时血浆降钙素基因相关肽含量与病情程度相一致。结论:血浆降钙素基因相关肽参与了哮喘的急性发作和炎症的反应过程。对判定病情程度、疗效、探讨治疗对策有一定的价值。
Objective: To investigate the relationship between plasma calcitonin gene-related peptide and acute exacerbation of bronchial asthma. Methods: The levels of plasma calcitonin gene-related peptide in patients with acute asthma and remission were determined, and normal controls were established. Results: The levels of plasma calcitonin gene-related peptide in patients with acute exacerbation of bronchial asthma were significantly increased (P <0.001), and the levels of plasma calcitonin gene-related peptide Consistent. CONCLUSION: Plasma calcitonin gene-related peptide is involved in the acute episodes of asthma and inflammatory response. To determine the extent of illness, curative effect, to explore treatment strategies have some value.