【摘 要】
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Objective To evaluate the effectiveness of transdermal fentanyl (Durogesic) in the treatment of cancer pain. Methods 30 cases of patients with moderate to sever
【机 构】
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First Affiliated Hospital of Dalian Medical University,Dalian 116011,China
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Objective To evaluate the effectiveness of transdermal fentanyl (Durogesic) in the treatment of cancer pain. Methods 30 cases of patients with moderate to severe cancer pain were treated using Durogesic,and 30 patients were treated using sustained release hydrochloride morphine tablets as control group.Durogesic began from the dosage of 25 μ g/h to individual doses,and hydrochloride morphine began from 30 mg to individual doses.The duration of treating time was 3 weeks.Results The response rate of pain relief was 80.0% in Durogesic group and 83.3% in hydrochloride morphine group,respectively; Quality of life scores were(27.27± 3.53)before treatment and(32.67± 2.88)after treatment(P<0.05) in Durogesic group;The main side effect were dizziness,nausea and somnolence.Conclusion Durogesic is effective in the treatment of cancer pain,it can improve the quality of life scores and the side effect is mild to tolerate.
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