扁平苔藓皮损中MMP-2、MMP-9、TIMP-1的表达

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目的:研究扁平苔藓皮损中MMP-2、MMP-9、TIMP-1在扁平苔藓皮损中的表达和意义,分析其表达与扁平苔藓的关系。方法:用免疫组化的方法检测30例扁平苔藓组织及30例正常组织中MMP-2、MMP-9、TIMP-1的表达,采用RT-PCR的方法检测TIMP-1mRNA在10例LP皮损和8例正常皮肤组织中的表达情况。结果:MMP-2、MMP-9、TIMP-1的表达以胞浆中着黄色或棕黄色颗粒为阳性,用积分光密度(integrated optical density, IOD)值的大
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