City is the region affected most frequently and acutely by human behaviors. Thus the natural landscape system of city varies markedly and becomes weak. In recent years, the LUCC of city has become a foreland and hotspot in research. This paper firsrt reviews the study on this subject, concludes previous theory and method and then brings forward a framework for analysis. The study is based on landscape ecology while backed up by GIS、 classic Statistics and Geostatistics. It applies data analysis to study the dynamic change and characteristic of land use from the lay of citydistrictspecial section and gets the rule of Guangzhou land use. The human force represented by city center and the natural force represented by exurb act and restrict on each other. The result is that the more closed the region is to city center ,the more it is affected by human force. On the Opposite, the more closed the region is to exurb, the more it is affected by natural force. The special pattern of Guangzhou land use is just the product of the collision of human force and natural force. This paper has analyzed the characteristic, evolvement and impact of land use of Guangzhou. It not only provides gist for future development programming, but also is valuable for other city in our country.