The exploration of RNA methylation was rejuvenated in the second decade of this century with the discovery of FTO as m6A demethylase in cells,which uncovered that RNA methylation is a dynamic and reve
DNA guanine-rich sequences can form non-canonical secondary structures known as G-quadruplexes.It has been suggested that DNA G-quadruplexes are involved in several key biological processes and variou
Controlled drug release systems can enhance the safety and availability but avoid the side effect of drugs.Herein,we use the concept of DNA complementary base pairing rules in biology to design and pr
Exploring of binding diversity of small molecule to G-quadruplex is very interesting for clarifying their relationship between function and structure-activity,to solve the problems NMR technology is a
Owing to the complicated physiological microenvironment,nanosystems designed with the possibility of noninvasive real-time monitoring the therapeutic progression in the second near-infrared channel(NI