Divergence of MEG Defined Expressive and Receptive Language in Patients with Medically Refractory Pa

来源 :BIT`s 3rd Annual World Congress of NeuroTalk-2012(2012第三届国际神 | 被引量 : 0次 | 上传用户:sunmoon
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Patients with medically refractory partial epilepsy who are considered to be candidates for resective epilepsy surgery frequently undergo various tests to assess language dominance and memory including neuropsychometric testing, Angio-WADA and direct cortical stimulations as to minimize resection of eloquent cortex.Language shifting has been described in patients with childhood onset epilepsy and may have an implication on surgical approach.Neuroimaging studies have shed a light on cortical language organization, with recent findings implicating left and right temporal lobes in speech converging to a left dominant pattern.Attention to presumptive non dominant lobe language mapping is not part of routine language protocols.We use a large array 148 channel biomagnetometer (MEG, 4D Neuroimaging) and multiple tasks (Auditory Word Recognition, Visual Verb Generation and Picture naming) in candidates for resective epilepsy surgery to investigate cortical organization for receptive and productive language function.Laterality indices were calculated.In our cohort 27% demonstrated discordant receptive and productive language with leftward laterality for the Verb generation task, tapping productive speech rightward laterality for the word recognition task tapping receptive language processing.Receptive and Expressive language may have divergent hemispheric dominance in patients with medically refractory partial epilepsy.Right sided receptive language dominance may have implications for surgical planning.MEG with multiple language tasks may have advantages as compared to other tests that sometimes may not assess independently productive and expressive speech.These finding were confirmed by Angio-WADA and direct cortical stimulations.
其他文献
为加快我国住宅与建筑科技成果的产业化、市场化和国际化,推动我国住宅与建筑业科技进步,全面展示我国2000年小康住宅示范工程和城市住宅试点小区的巨大成就,经中国国际高新
CommWorks公司近日宣布为VerizonWireless公司的1xRTTExpressNetwork提供数据网络设备。VerizonWireless是美国最大的无线通信供应商 ,采用Comm Works公司的无线数据接入技术来提高其全国性Ex pres CommWorks recently announced the provision of data
  After four weeks in a vegetative state, the patient is classified as in a persistent vegetative state.It is a diagnosis of some uncertainty because a persis
会议
安捷伦科技、北电网络和杰尔就城域网密集波分复用(DWDM)光网络系统中使用的可热插拔2.5Gbit/s(OC-48)收发模块达成一项多边协议(MSA)。根据这项协议开发的收发模块,可以改善
来信《中华魂》编辑部同志:最近,我在《炎黄春秋》2010年第3期读到董健教授《个人主义与公民社会》一文(见复印件),感到这真是一篇令人惊讶的奇文。这位标明是南京大学前副