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  5. Folid acid supplementation during pregnancy protects against lipopolysaccharide-induced teratogenici

Folid acid supplementation during pregnancy protects against lipopolysaccharide-induced teratogenici

来源 :全国卫生毒理学术研讨会 | 被引量 : 0次 | 上传用户：yong5665
【摘 要】
：
Lipopolysaccharide (LPS) is associated with adverse developmental outcomes,including preterm delivery,fetal death,teratogenicity,and intra-uterine growth restriction.The aim of the present study was t
【作 者】
：
Mei Zhao Yuan-Hua Chen Xue Chen Xu-Ting Dong Jun Zhou Hua Wang Zhen Wang Cheng Zhang De-Xiang Xu 
【机 构】
：
Department of Toxicology,Anhui Medical University,Hefei,China
【出 处】
：
全国卫生毒理学术研讨会
【发表日期】
：
2014年9期
【关键词】
：
Folic acid lipopolysaccharide developmental toxicity teratogenicity inflammation 
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　　Lipopolysaccharide (LPS) is associated with adverse developmental outcomes,including preterm delivery,fetal death,teratogenicity,and intra-uterine growth restriction.The aim of the present study was to investigate the effects of folic acid on LPS-induced teratogenicity.All pregnant mice except controls were intraperitoneally (i.p.) injected with LPS (20 μg/kg) daily from gestational day (GD)8 to GD12.Folic acid was administered in three different modes.
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