血管性非痴呆认知损害患者神经心理学特征、中医证候及其与危险因素的相关性研究

来源 :世界中医药学会联合会第二届老年医学专业委员会换届会暨2015学术年会 | 被引量 : 0次 | 上传用户:houjz
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  目的 研究血管性非痴呆认知损害(VCIND)患者神经心理学特征、中医证候与危险因素的相关性,为血管性认知损害临床防治提供依据.方法:在西安咸阳地区6大社区招募中老年志愿者,通过相关神经心理学量表测试、中医证候量表评定以及必要的医学检查,筛选出71名血管性非痴呆认知损害患者,分析患者的神经心理学特征、中医证候、血管性危险因素及其相关性.结果 血管性非痴呆认知损害患者MMSE延迟回忆、MMSE总分、MOCA注意力得分与肾精亏虚呈负相关(p值分别为0.017、0.043、0.041);MMSE视空间、MOCA注意力得分与瘀血阻络呈负相关(p值分别为0.026、0.024);MOCA注意力与气血两虚呈负相关(p值为0.046);肾精亏虚为血管性非痴呆认知损害患者中比例最高的证候类型(占67.60%).血管性非痴呆认知损害患者MOCA视空间/执行功能、MOCA总分与脑卒中呈负相关(p值分别为0.036, 0.033);MMSE定向力与糖尿病呈正相关(p值为0.046);高血压病为血管性非痴呆认知损害患者中比例最高的危险因素(占71.83%).结论 肾精亏虚、瘀血阻络、气血两虚为血管性非痴呆认知损害患者的主要证候类型;高血压是血管性非痴呆认知损害患者的主要血管性危险因素;脑卒中对血管性非痴呆认知损害患者神经心理学特征影响最为显著.
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