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  5. The Development of a Nanocrystalline Apatite Reinforced Crosslinked Hyaluronic Acid-N,O-Carboxymethy

The Development of a Nanocrystalline Apatite Reinforced Crosslinked Hyaluronic Acid-N,O-Carboxymethy

来源 :第七届亚澳复合材料会议 | 被引量 : 0次 | 上传用户：kentron
【摘 要】
：
In this study, a water-soluble chitosan derivative, N,O-carboxymethylchitosan (NOCC) has been synthesized.Hyaluronic acid (HA) could evolve into a better cross-linked hydrogel by conjugating with NOCC
【作 者】
：
Fwu-Long Mi Shu-Huei Yu Deh-Wei Tang Hao-Ying Hsieh Tzu-Hung Kuo Wei-Ren Wang 
【机 构】
：
Department of Biotechnology,Vanung University Dep
【出 处】
：
第七届亚澳复合材料会议
【发表日期】
：
2010年4期
【关键词】
：
chitosan hyaluronic acid apatites bone cement NOCC 
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　　In this study, a water-soluble chitosan derivative, N,O-carboxymethylchitosan (NOCC) has been synthesized.Hyaluronic acid (HA) could evolve into a better cross-linked hydrogel by conjugating with NOCC, using carbodiimide as a cross-linker, therefore decreased the swelling capability and increased the resistance against hyaluronidase degradation of the HA-based hydrogels.
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