目的 在大鼠模型基础上,观察PEDF靶向给药对子宫内膜异位病灶生长及新生血管形成相关因子的影响,并比较不同药物载体的效果.方法 建立子宫内膜异位症大鼠模型,并按计算机随机数字法分为5组,根据干预措施的不同分别为:(1)对照组(G1):单纯造模,仅给予生理盐水腹腔注射;(2) PEDF组(G2):直接给予PEDF蛋白(25μg/kg)腹腔注射;(3)给予免疫纳米脂质体包裹的PEDF质粒(G3).
Background Endometriosis is an estrogen-dependent disease, and aromatase is the key enzyme for estrogen biosynthesis.Elevated levels of aromatase mRNA have been found in ovarian endometriomas.There is
Objective To investigate the clinicopathologic features, the management, and the prognosis of villoglandular papillary adenocarcinoma (VGPA) of the uterine cervix.Methods Four Clinical cases of VGPA w
目的 探讨人脐带间充质干细胞(human umbilical cord mesenchymal stem cells,HUCMSCs)移植治疗雌鼠压力性尿失禁(stress urinary incontinence,SUI)的可行性和有效性.方法 采用气囊压迫分娩大鼠阴道壁模拟产伤并行双侧卵巢切除建立SD大鼠压力性尿失禁模型,建模两月后行转染pEGFP-N1质粒的间充质干细胞(MSCs)尿道周围注
Background To investigate the prenatal ultrasonic manifestations of fetal congenital high airway obstruction syndrome (CHAOS).Methods We compared the ultrasonographic characteristics of five fetuses w
Antimicrobial resistance has arisen across the globe in both nosocomial and community settings as a consequence of widespread antibiotic consumption(l).Achievements in modern medicine, such as major s
Background Conservative "hands on" birth manual perineal protection (MPP) is one of the most common OB procedures-60％ of births in 1979, 24.5％ in 2004 in American and that was 90％ in China at the same
Background A 38-year old female received NIPT at 13+5 weeks gestation following a previously described protocol (1).The results suggested a potential risk of trisomy 21.After genetic counseling, the p
目的 研究分析子宫憩室的临床特点为治疗方式的选择提供依据.方法 回顾性分析2012年1月至2014年1月我院诊治的46例子宫憩室患者的临床资料.结果 子宫疤痕部位憩室组与非子宫憩室组比较,两者疤痕部位肌层厚度的差异有统计学意义(P＜0.05).患者症状与子宫憩室的大小有关,憩室的长度、宽度差异有统计学意义(P＜0.05).不同治疗方式的选择与有无临床症状有关,差异有统计学意义(P＜0.05).修复
Background The purpose of this study was to demonstrate the feasibility of single port laparoscopic surgery (SPLS) for the treatment of adnexal lesions by comparing with conventional laparoscopic surg