FGF/FGFR Pathway and its Targeting in Renal Cell Carcinoma

来源 :2011第三届中国北京抗体大会 | 被引量 : 0次 | 上传用户:zhoubin506
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  Fibroblast growth factor (FGF) receptor (FGFR) signaling is required for progression of many tumors but this pathway has not been well studied as a prognostic factor or potential therapeutic target in renal cell carcinoma (RCC).In our studies, we evaluated preliminary role of FGF/FGFR pathway in RCC.Our studies have demonstrated a high expression of FGFR1 in human primary and metastatic renal cell carcinoma.
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