【摘 要】
：
In order to improve the extraction yields of resveratrol and emondin obtained by supercritical CO2 extraction (SCE) different solubilizers were added in the supercritical CO2 extraction process.Resver
【机 构】
：
Department of Pharmacy,Zhujiang Hospital,Southern Medical University,Guangzhou,China,510282
论文部分内容阅读
In order to improve the extraction yields of resveratrol and emondin obtained by supercritical CO2 extraction (SCE) different solubilizers were added in the supercritical CO2 extraction process.Resveratrol and emondin were extracted from Polygonum cuspidatum by SCE with different solubilizers,including AOT,PVP k-90,Poloxamer 188 and Tween 80,at extraction pressure 25 MPa and extraction temperature 50℃.The results show that resveratrol was hardly extracted by SCE with ethanol as modifier,but AOT,PVP k-90,Poloxamer 188 and Tween 80 could enhance the extraction yield of resveratrol significantly,while the yield of emodin was influenced gently by using these solubilizers.Based on the comparison of SCE and Heat Reflux Extraction,the advantage of SCE is less extraction time at lower operating temperature without using large amount of organic solvent.The yields of resveratrol and emondin extraction from Polygonum cuspidatum by SCE can be improved by introducing AOT,PVP k-90 and Poloxamer 188 into supercritical CO2.
其他文献
Various epidemiologic studies in recent years have indicated that light/moderate alcohol consumers have lower risks of nerve degenerative disease,suggesting that ethanol have neuroprotective effect.Et
目的:结合响应面分析法,研究复方金钱草中君药的半仿生提取工艺最佳条件.方法:利用响应面分析法,测定各种半仿生提取液中的总黄酮、总糖含量和干浸膏重量并进行综合比较,以综合评分为响应值作响应面和等高线,分析提取工艺条件.结果:复方金钱草中三种药材半仿生提取最佳条件为:温度100℃、料液比1 g∶35 ml,提取3次,三次水煎液pH值分别为4.0、7.0和8.5,总提取时间为2.5小时.在该条件下,总黄
To evaluate the efficacy and safety of moxifloxacin monotherapy for treatment of complicated intra-abdominal infections.PubMed,EMBASE,Science Direct,Clinical-Trials.gov and Cochrane Central Register o
目的:利用腺病毒载体技术,研究目的基因修饰的人源性PBMC细胞来源的树突状细胞对抗HIV-1的感染.方法:将目的基因CCR5△32,CCR5siRNA,HIV-1 poli和HIV-1 inti整合到腺病毒载体上,在体外将人源性PBMC细胞诱导为树突状细胞.用免疫印迹检查目的基因的表达情况.并且检测修饰后的细胞对HIV-1病毒的抵抗情况.结果:用重组腺病毒修饰后的细胞中,CCR5△32的表达明显增
Aim:To identify the characteristics of recombinant adenovirus modified PBMC-derived dendritic cells and their resistance to HIV-1 infection.Method:The recombinant adenovirus vector was integrated with
目的:淋病是目前世界上发病人数最多的生殖感染之一。由淋球菌引起。考察姜黄素的体外抑制淋球菌的活性.方法:以最小抑菌浓度、抑菌圈为指标对姜黄素的体外抑菌效果进行分析.结果:姜黄素在体外条件下对淋球菌的最小抑菌浓度是l00mg/ml,以最小抑菌浓度作抑菌圈试验,其对淋球菌的抑菌圈直径为13mm.结论:姜黄素在体外可以抑制淋球菌的活性.
目的:从葛洪《肘后备急方》对熏洗疗法药方的记载情况探讨魏晋南北朝时期熏洗疗法的发展概况和葛洪对熏洗疗法的贡献.方法:从葛洪《肘后备急方》熏洗疗法的药方来源及分布、药方形式和治疗方法及疾病种类等方面进行文献整理分析.结果:熏洗疗法经过秦汉时期的理论形成和应用推广,至魏晋南北朝时期在熏洗形式和治疗方法已形成较为完整的理论体系,在外、内、妇、骨伤、皮肤、五官等临床各科均有广泛使用,并且很多熏洗方药组方科
目的：建立同时分离测定虎杖根中大黄酸、大黄素、大黄酚和大黄素甲醚4种蒽醌类含量的反相高效液相色谱方法.方法：采用Kromasil-C18色谱柱(4.6mm×150mm,5μm),流动相为甲醇-水(85∶15,v/v),流速为0.8mL·min-1,检测波长为430 nm,柱温为30℃.结果：在本实验条件下,4种蒽醌类成分有很好的分离,大黄酸、大黄素、大黄酚、大黄素甲醚的进样量与峰面积分别在0.07
目的：了解钙拮抗类抗高血压药致心脏不良反应(ADR)的发生情况,探讨其发生规律,指导临床合理用药,保证用药安全有效.方法：对广东省2002年1月-2012年06月上报的63例钙拮抗药发生的ADR进行统计分析.结果：心脏ADR的发生与性别关系不大,与年龄关系密切,41岁以上的中老年患者居多；ADR发生时间多集中在1天内；二氢吡啶类钙拮抗药引起的心脏ADR比例最高(60例,95.24％)；临床表现以心
背景和目的 中药十八反是中医界沿袭数千年的用药禁忌.有研究表明,甘草与反药合用前后对细胞色素P450具有不同的调控作用.令人感兴趣的是p-糖蛋白(P-gp)的底物特异性很大程度上与细胞色素P450同工酶(CYP3A1-3)相似,二者有很多重叠的底物.那么,这些反药对合用前后是否也有可能对肠粘膜P-gp产生不同的调节作用,这可能是中药十八反反药对合用引起临床上产生毒性的原因.文献检索表明,目前国内外