Oxidative stress mediates increased myocyte autophagy in pressure overload-induced left ventricular

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:yannini01
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Background: Myocyte autophagy is increased in cardiac hypertrophy.However,the underlying mechanisms remain unclear.In this study,we tested the hypothesis that oxidative stress mediates increased myocyte autophagy in pressure overload-induced left ventricular(LV)hypertrophy in rats.
其他文献
Aims: To examine the expression patterns of hydrogen sulphide-(H2S-)producing enzymes in ischaemic heart tissue and plasma levels of H2S after 2 weeks of NaHS treatment after myocardial infarction(MI)
Rationale: Vascular smooth muscle cell(VSMC)phenotypic switching proceeds the pathogenesis of abdominal aortic aneurysm(AAA).X-box binding protein 1(XBP1),a basic-region leucine zipper(bZIP)transcript