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5. Structural basis of highly specific interaction between Nephrin and MAGI1 in slit diaphragm assembly

Structural basis of highly specific interaction between Nephrin and MAGI1 in slit diaphragm assembly

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：aini412319016

【摘 要】

：

Slit diaphragm(SD)is a specialized adhesion junction between the opposing podocytes,establishing the final filtration barrier to prevent passage of proteins from the capillary lumen into the urinary s

【作 者】

：

Zhuangfeng Weng Yuan Shang Zeyang Ji Fei Ye Lin Lin Rongguang Zhang Jinwei Zhu 

【机 构】

：

State Key Laboratory of Molecular Biology,CAS Center for Excellence in Molecular Cell Science,Shangh

【出 处】

：

中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

nephrin nephrotic syndrome glomerular filtration barrier cell adhesion 

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　　Slit diaphragm(SD)is a specialized adhesion junction between the opposing podocytes,establishing the final filtration barrier to prevent passage of proteins from the capillary lumen into the urinary space.Nephrin is the key structural and signaling adhesion molecule prominently expressed in SD.

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