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目的：沙门氏菌病属于重要的食源性致病菌之一，经常通过污染的水和食物引起人类疾病。沙门氏菌的致病性与其毒力岛基因密切相关。因此，构建沙门氏菌单个或多个毒力岛的基因缺失株，并评估这些毒力岛对沙门氏菌致病性的影响以及在鸡体内诱导免疫应答变化是非常重要的。
肠炎沙门氏菌三种主要毒力岛基因缺失株的构建及其免疫效力研究
【摘 要】
：
目的：沙门氏菌病属于重要的食源性致病菌之一，经常通过污染的水和食物引起人类疾病。沙门氏菌的致病性与其毒力岛基因密切相关。因此，构建沙门氏菌单个或多个毒力岛的基因缺失株，并评估这些毒力岛对沙门氏菌致病性的影响以及在鸡体内诱导免疫应答变化是非常重要的。
【机 构】
：
中国农业科学院哈尔滨兽医研究所兽医生物技术国家重点实验室/动物细菌病研究室 中国农业科学院哈尔滨兽
【出 处】
：
中国免疫学会第十届全国免疫学学术大会
【发表日期】
：
2015年10期
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