纳米氧化铜对贝类免疫系统的毒性及机制研究

来源 :全国环境纳米技术及生物效应学术研讨会 | 被引量 : 0次 | 上传用户：mumurong

【摘要】

：

目前，关于纳米氧化铜颗粒(CuO NPs)毒性效应的研究已很多，但是CuO NPs 对海洋生物血细胞的致毒机制尚不清楚。本研究以原代培养的海洋贝类血淋巴细胞为研究对象，运用流式细胞术和DNA 损伤技术分析氧化铜纳米颗粒(NPparticle)和释放的铜离子(NPion)对贝类免疫系统血淋巴细胞的短期体外胁迫效应，然后利用整合生物标物法量化尺寸效应和离子效应的贡献率，明确CuO NPs 对细胞致毒的

【作者】

：

孙雪梅夏斌陈碧鹃曲克明朱琳

【机构】

：

中国水产科学研究院黄海水产研究所农业部海洋渔业资源可持续利用重点实验室山东省渔业资源与生态环境重点实验室,青岛 266071

【出处】

：

全国环境纳米技术及生物效应学术研讨会

【发表日期】

：

2016年7期

【关键词】

：

纳米氧化铜铜离子血淋巴细胞整合生物标志物

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纳米氧化铜对贝类免疫系统的毒性及机制研究

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