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GPCR 在细胞内外的信号传导中起着关键作用目前市场上,50％的药物都是以GPCR为靶标。其中A类GPCR 是研究得最为广泛,有大量实验研究表明A类GPCR 存在着二聚体,它是除单体之外一个潜在的新的药物靶标。然而二聚体结构、动力学性质以及相关的生物功能目前还存在着争议。
GPCR二聚体结构和动力学性质的弹性网络模型分析
【摘 要】
：
GPCR 在细胞内外的信号传导中起着关键作用目前市场上,50％的药物都是以GPCR为靶标。其中A类GPCR 是研究得最为广泛,有大量实验研究表明A类GPCR 存在着二聚体,它是除单体之
【机 构】
：
四川省成都市四川大学化学学院,610064
【出 处】
：
第十三届全国计算机化学学会会议
【发表日期】
：
2015年期
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